On August 12, 2026, the Government of Canada added 656 substances from the Revised In Commerce List (R-ICL) to the Domestic Substances List (DSL) under the authority of the modernized Canadian Environmental Protection Act, 1999 (CEPA). 

The R-ICL is an administrative list of substances found in products regulated under the Food and Drugs Act that were in Canadian commerce between January 1, 1987, and September 13, 2001. Under CEPA, substances on the R-ICL may be added to the DSL once specific eligibility criteria have been met.

With their addition to the DSL, these 656 substances have been removed from the R-ICL and are no longer subject to the New Substances Notification Regulations. This change may reduce regulatory requirements for companies using these substances in products regulated in Canada. For more such updates, contact us.