174 Substances Added to the Non-Domestic Substances List (NDSL)

by | Apr 15, 2026 | Canadian Quality Assurance, Canadian Regulatory, Health Canada Updates, Importation of NHPs, Natural Health Products, Our View

On March 24th, a significant update was published in the Canada Gazette, Part I, Volume 160, Number 14: an Order Amending the Non-domestic Substances List (NDSL).

This latest order officially adds 174 substances to the NDSL. For companies manufacturing or importing chemical substances into Canada, this update provides a more streamlined regulatory environment.

Substances listed on the NDSL benefit from:

  • Higher Volume Thresholds: Allowing for larger quantities to be handled before specific notification requirements are triggered.
  • Streamlined Notifications: Providing a more direct and efficient path to compliance compared to substances not appearing on the list.

It is critical for stakeholders to remain aware of NDSL additions, as these changes can directly impact your notification strategy and timelines. Utilizing substances on this list often results in reduced administrative burden and faster processing for your chemical notifications.

If you need any assistance with these associated regulatory updates, our team is here to assist you.